1 Result for "

dantrolene alternative

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "dantrolene alternative" in MCE Product Catalog:

Cat. No.: HY-141564
CAS No.: 2837939-81-6
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke .
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