RyR1-IN-1
RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke.
For research use only. We do not sell to patients.
- CAS No.: 2837939-81-6
- Formula: C19H22NNaO5
- Molecular Weight:367.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
Chemical Information
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CAS No. 2837939-81-6
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Molecular Weight 367.37
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Formula C19H22NNaO5
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SMILES
O=C1C(C(O[Na])=O)=CN(CCCCCCCC)C2=CC3=C(OCO3)C=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)