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RyR1-IN-1

RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke.

For research use only. We do not sell to patients.

  • CAS No.: 2837939-81-6
  • Formula: C19H22NNaO5
  • Molecular Weight:367.37
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • RyR1-IN-1 Chemical Structure
    RyR1-IN-1 Chemical Structure
CAS No.: 2837939-81-6
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All Calcium Channel Isoforms

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  • RyR1-IN-1 Chemical Structure
    RyR1-IN-1 Chemical Structure
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  • RyR1-IN-1