4 Results for "

fish zebrafish

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "fish zebrafish" in MCE Product Catalog:

Isotocin
Isotocin
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Cat. No.: HY-P4184
CAS No.: 550-21-0
Synonyms: (Ser4,Ile8)-Oxytocin
Target:  

Endogenous Metabolite Aminopeptidase

Research Areas:  

Neurological Disease

Isotocin is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin exerts biological effects by binding to its homologous isotocin receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Picolinafen
Picolinafen
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Cat. No.: HY-W711035
CAS No.: 137641-05-5
Synonyms: AC 900001
Target:  

p38 MAPK PI3K Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Cytochrome P450

Research Areas:  

Inflammation/Immunology

Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD50 value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis [1][2].
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Tricaine-d5 methanesulfonate
Tricaine-d5 methanesulfonate
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Cat. No.: HY-W011777S
Synonyms: MS-222-d5
Tricaine-d5 methanesulfonate is the deuterium labeled Tricaine methanesulfonate (HY-W011777). Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .
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Isotocin acetate
Isotocin acetate
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Cat. No.: HY-P4184A
Synonyms: (Ser4,Ile8)-Oxytocin acetate
Target:  

Endogenous Metabolite Aminopeptidase

Research Areas:  

Neurological Disease

Isotocin acetate is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin acetate exerts biological effects by binding to its homologous Isotocin acetate receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin acetate promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin acetate regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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