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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
fused-ring molecule
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "fused-ring molecule" in MCE Product Catalog:
Cat. No.: HY-W010610
CAS No.: 5239-82-7
Target:
Research Areas:
2-Cyclopropylacetic acid is a substrate. 2-Cyclopropylacetic acid can produce a ring-opening product, which serves as an important precursor for the preparation of fused-ring molecules .
Cat. No.: HY-L0120V
170,269 compounds
“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.
Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).
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Protocols
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