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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
human SK1
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "human SK1" in MCE Product Catalog:
Cat. No.: HY-137952
CAS No.: 875755-39-8
Target:
Research Areas:
NS8593 is an SK channel (small conductance Ca 2+-activated K+ channels) inhibitor. NS8593 reversibly inhibited recombinant SK3-mediated currents (human SK3 and rat SK3). NS8593 inhibits all the SK1-3 subtypes Ca 2+-dependently (Kd = 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca 2+). NS8593 does not affect the Ca 2+-activated K channels of intermediate and large conductance (hlk and hBK channels, respectively). NS8593 can also inhibit TRPM7 (melastatin-related TRP cation channel 7) (IC50 = 1.6 mM). NS8593 can be used for the study of central nervous system (CNS) related diseases .
Cat. No.: HY-P73631
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPHK1; SK 1; Sphingosine Kinase 1; Sphingosine Kinase; SPHK; SPHK1 Protein; Acetyltransferase SPHK1; SK1; SPK 1; SPK
Species:
Source:
Cat. No.: HY-P702765
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPHK1; SK 1; Sphingosine Kinase 1; Sphingosine Kinase; SPHK; SPHK1 Protein; Acetyltransferase SPHK1; SK1; SPK 1; SPK
Species:
Source:
Cat. No.: HY-124368
CAS No.: 1491909-40-0
Target:
Research Areas:
RB-042 is a SK1 and SK2 inhibitor with IC50 values of 5.3 μM and 5.0 μM, respectively. RB-042 is applicable to the research of inflammatory diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
