3 Results for "

mk866

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "mk866" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-50908
CAS No.: 572924-54-0
Synonyms: mk-8669; Deforolimus; AP23573
Target:  

mTOR Autophagy Bacterial

Research Areas:  

Cancer

Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells .
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Cat. No.: HY-W727728
CAS No.: 1544739-75-4
Research Areas:  

Metabolic Disease

MK-8666 is a potent and selective partial GPR40 agonist (EC50 = 0.54 nM for human GPR40). MK-8666 shows selectivity over GPR119, GPR43, GPR41, GPR120, and other G-protein-coupled receptors (GPCRs). MK-8666 reduces glucose in the rodent. MK-8666 can be used for type 2 diabetes research [1][2].
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Cat. No.: HY-141653
CAS No.: 2056254-98-7
Research Areas:  

Metabolic Disease

MK-8666 (tromethamine) is a GPR40 agonist. MK-8666 (tromethamine) can be used in the research of type II diabetes .
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