572924-54-0
572924-54-0
Chemical Structure
Ridaforolimus
Synonym(s): MK-8669; Deforolimus; AP23573
- CAS No.: 572924-54-0
- Formula:C53H84NO14P
- Molecular Weight:990.21
InChIKey: BUROJSBIWGDYCN-GAUTUEMISA-N
SMILES: O=C(C([C@](O[C@]1([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H]2C)OC)([C@@H](CC1)C)O)=O)N(CCCC3)[C@]3([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@H](C)C2)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H](CC[C@H]4OP(C)(C)=O)C[C@H]4OC)=O
Biological Activity: Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Ridaforolimus | 99.75% | Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells. | ||||||||||||||||||||
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