1 Result for "

monkeypox clade IIb

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "monkeypox clade IIb" in MCE Product Catalog:

Cat. No.: HY-183592
Research Areas:  

Infection

Anti-virus agent 2 is an orally active and selective anti-orthopoxvirus (poxvirus) agent, with EC50 values of 6.1 μM and 47.1 μM against VTT-Fluc and MPXV clade IIb, respectively. Anti-virus agent 2 covalently binds to viral A17L protein and mRNA methyltransferase, blocks viral membrane fusion and intracellular biosynthesis, and acts on multiple stages of the viral replication cycle. Anti-virus agent 2 achieves viral inhibition in nude mouse models. Anti-virus agent 2 can be used for the research of orthopoxvirus infections such as monkeypox and smallpox .
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