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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
mouse skin abscess model
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "mouse skin abscess model" in MCE Product Catalog:
Cat. No.: HY-184584
Research Areas:
Antibacterial agent 358 is an antibacterial agent. Antibacterial agent 358 selectively interacts with PG on bacterial cell membranes, causing membrane damage. Antibacterial agent 358 induces bacterial cell membrane depolarization, increased membrane permeability and leakage of intracellular components. Antibacterial agent 358 inhibits biofilm formation and disrupts established biofilms. Antibacterial agent 358 reduces bacterial load and alleviates tissue inflammation in a mouse skin abscess model. Antibacterial agent 358 can be used in research related to Gram-positive bacterial infections and skin abscesses .
Cat. No.: HY-182798
Research Areas:
Antibacterial agent 337 is an antibacterial agent. Antibacterial agent 337 specifically interacts with PG in bacterial cell membranes, triggering membrane disruption, membrane depolarization, increased permeability, cytoplasmic leakage, ROS accumulation and rapid bacterial death. Antibacterial agent 337 inhibits biofilm formation and disrupts mature biofilms. Antibacterial agent 337 exhibits potent in vivo antibacterial efficacy in a mouse model of Staphylococcus aureus skin abscess. Antibacterial agent 337 can be used in studies of Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus infections, vancomycin-resistant Enterococcus faecalis infections and bacterial biofilm infections .
Cat. No.: HY-182816
CAS No.: 3080330-34-0
Target:
Research Areas:
Topoisomerase I-IN-22 is an inhibitor of MRSA DNA Topoisomerase I with an IC50 of 0.85 μg/mL. Topoisomerase I-IN-22 can specifically disrupt the cell membrane structure of MRSA, enter the interior of bacteria and inhibit the activity of DNA Topoisomerase I, thereby interfering with the processes of DNA replication and transcription. Topoisomerase I-IN-22 can be used for the research of MRSA infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
