2 Results for "

negative allosteric modulation

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "negative allosteric modulation" in MCE Product Catalog:

Cat. No.: HY-103320B
Purity:  99.07%
Target:  

CaSR

Research Areas:  

Metabolic Disease

(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca 2+-induced accumulation of [ 3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment .
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Cat. No.: HY-108668
CAS No.: 873398-67-5
Target:  

P2X Receptor

Research Areas:  

Others

TC-P 262 is a potent P2X3 inhibitor. TC-P 262 shows inhibition by bindings to hP2X3. TC-P 262 has the potential for the research of rheumatoid arthritis, cough, and pain .
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