1 Result for "

non-covalent antigen-specific binding

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "non-covalent antigen-specific binding" in MCE Product Catalog:

Cat. No.: HY-P990610

Target:  

Akt mTOR PI3K

Research Areas:  

Cancer

KHK-2898 is a monoclonal antibody targeting CD98, which binds to the extracellular domain of CD98 on the tumor cell membrane in a non-covalent antigen-specific mode. KHK-2898 can disrupt the heterodimeric complex formed by CD98 with LAT1 and xCT light chains, reduce the amino acid uptake capacity of tumor cells, block the PI3K/AKT/mTOR proliferative signaling cascade, and mediate antibody-dependent cytotoxicity. KHK-2898 can be used for cancer-related research. The isotype control of KHK-2898 can be found in Human IgG1 kappa, Isotype Control (HY-P99001) .
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