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6
6 Cited Publications
Cat. No.: HY-138646
CAS No.: 86828-69-5
Synonyms: Poly(dA:dT) sodium
Research Areas:  

Inflammation/Immunology

Poly(deoxyadenylic-thymidylic) acid (Poly(dA:dT)) sodium is a double-stranded DNA stimulant. Poly(deoxyadenylic-thymidylic) acid sodium is recognized by the intracellular DNA sensor DDX41 and activates the innate immune pathway via the adaptor protein STING, inducing the production of cytokines such as type I interferons. Poly(deoxyadenylic-thymidylic) acid sodium also serves as an in vitro transcription template for free RNA polymerase .
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