1 Result for "

opiate dependence

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "opiate dependence" in MCE Product Catalog:

Cat. No.: HY-B1052
CAS No.: 21498-08-8
Synonyms: Baq-168; MDL-14042
Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal .
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