2 Results for "

peripheral KOR activation

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "peripheral KOR activation" in MCE Product Catalog:

Cat. No.: HY-P5907
CAS No.: 2883653-86-7
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator with a Ki of 21 nM and an EC50 of 45 nM. Helianorphin-19 exhibits strong KOR-specific peripheral analgesic activity in a mouse model of chronic visceral pain .
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Cat. No.: HY-178720
CAS No.: 2168573-03-1
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

SHR0687 is a selective tetrapeptide kappa opioid receptor (KOR) agonist with an EC50 of 0.53 pM. SHR0687 displays high potency and selectivity over MOR and DOR, with negligible blood-brain barrier penetration. SHR0687 activates KOR specifically, leading to potential modulation of neurological pathways without significant central nervous system effects. SHR0687 can be used for the research of pain .
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