1 Result for "

primary mouse BMDM

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "primary mouse BMDM" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-157131
CAS No.: 2242724-49-6
Purity:  99.84%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes .
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