1 Result for "

rel-Talmapimod

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "rel-Talmapimod" in MCE Product Catalog:

Cat. No.: HY-10406B
CAS No.: 879132-01-1
Synonyms: rel-SCIO-469 hydrochloride
rel-Talmapimod (rel-SCIO-469) hydrochloride is an orally active and selective inhibitor of p38α MAPK with an IC50 of 9 nM. rel-Talmapimod hydrochloride inhibits the secretion of inflammatory factors (such as TNFα, IL-1β, IL-6, and VEGF) by suppressing the p38α MAPK pathway, and it also inhibits angiogenesis and osteoclast activation. rel-Talmapimod hydrochloride inhibits the growth of multiple myeloma cells and induces apoptosis. rel-Talmapimod hydrochloride can be used to study various hematological malignancies (such as multiple myeloma, myelodysplastic syndrome) .
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