1 Result for "

sodium-containing buffer

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "sodium-containing buffer" in MCE Product Catalog:

Cat. No.: HY-168366
CAS No.: 3222-88-6
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

R-6890 is a Brorphine-related opioid receptor antagonist that exhibits differential binding activities toward rat opioid receptors (IC50=4.6 nM (0.05 M Tris; pH 7.4) and 170 nM (0.05 M Tris+0.1 M NaCl)). R-6890 displaces bound labeled opioids from receptors, and its binding affinity is affected by environmental factors, decreasing in the presence of NaCl. R-6890 crosses the blood-brain barrier (BBB) and exerts analgesic effects in the warm water-induced tail-flick reflex model of male Wistar rats .
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