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1 Result for "
thyroparathyroidectomized rats
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "thyroparathyroidectomized rats" in MCE Product Catalog:
Cat. No.: HY-183495
CAS No.: 201215-10-3
Target:
Domaines de recherche:
A-75943 is a bone resorption inhibitor isolated from Streptomyces sp. SANK 61296, with protein synthesis toxicity. A-75943 inhibits bone resorption in vitro, and also suppresses the increase in serum calcium levels and the decrease in bone mineral density in thyroparathyroidectomized rats. A-75943 inhibits protein synthesis. High concentrations of A-75943 reduce the survival rate of osteoclasts on bone slices, while low concentrations have no effect on the survival rate or morphology of osteoclasts. A-75943 can be used for the research of osteoporosis and hypercalcemia .
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