1 Result for "

valine tRNA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "valine tRNA" in MCE Product Catalog:

Cat. No.: HY-180995
CAS No.: 428830-84-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

VARS1-IN-1 is a valyl-tRNA synthetase (VARS1) inhibitor with a Kd of 0.213 μM. VARS1-IN-1 suppresses VARS1’s tRNA aminoacylation activity, reduces charged levels of valine tRNAs and redues total protein synthesis rate. VARS1-IN-1 suppresses aggressive tumor growth and cell proliferation in PC3 prostate cancer xenograft models. VARS1-IN-1 can be used for the research of prostate cancer .
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