Med12 - mediator complex subunit 12 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 679693

Summary

Contributes to ubiquitin protein Ligase activity. Involved in protein ubiquitination. Part of ubiquitin Ligase complex. Human ortholog(s) of this gene implicated in FG syndrome; leiomyosarcoma; major depressive disorder; phobic disorder; and syndromic X-linked intellectual disorder Lujan-Fryns-type. Orthologous to human MED12 (mediator complex subunit 12). [provided by Alliance of Genome Resources, Apr 2022]

Med12 Products (3)

mRNA Protein Name
NM_001193292.2 NP_001180221.1 mediator of RNA polymerase II transcription subunit 12 isoform 2
NM_001414735.1 NP_001401664.1 mediator of RNA polymerase II transcription subunit 12 isoform 1
NM_001193292.1 NP_001180221.1 mediator of RNA polymerase II transcription subunit 12

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
12149480 RGD
Biological Process GO Annotation Evidence References Source
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
12149480 RGD
Cellular Component GO Annotation Evidence References Source
part of ubiquitin ligase complex IDA
IDA: Inferred from direct assay
12149480 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114965 TP-064 Inhibitor 99.29% Unkown
HY-100360 MS049 Inhibitor 98.0% Unkown
HY-RS08281 MED12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100360A MS049 dihydrochloride Inhibitor / Unkown
HY-RS08282 MED12L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18290 Med12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24768 Med12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med12 NCBI NCBI:9968