3 Results for "

p85 binding

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "p85 binding" in MCE Product Catalog:

261
261 Cited Publications
Cat. No.: HY-P0175
CAS No.: 1236188-16-1
Synonyms: 740YPDGFR; PDGFR 740Y-P
Target:  

PI3K Autophagy

Research Areas:  

Cancer

740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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Cat. No.: HY-P0175A
Synonyms: 740YPDGFR TFA; PDGFR 740Y-P TFA
Target:  

PI3K Autophagy

Research Areas:  

Cancer

740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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Cat. No.: HY-187155
CAS No.: 158778-21-3
Target:  

PI3K

Research Areas:  

Others

Cyclo (Gly-{Tyr (PO3H2)-Val-Pro-Met-Leu) is a binding peptide for the PI3K SH2 domain, as well as an inhibitory peptide for the mitogenic signal transduction-mediating domain. Cyclo (Gly-{Tyr (PO3H2)}-Val-Pro-Met-Leu) binds to the SH2 domain of the phosphorylated PI3K p85 subunit, and the spatial arrangement of its phosphotyrosine residue and methionine residue is associated with this interaction .
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