SPK-843
SPK-843 is an antifungal agent. SPK-843 shows inhibitory activity against A. fumigatus MF-13, A. flavus TIMM 0057, and A. niger TIMM 2814 with MICs of 0.5 μg/mL, 0.25 μg/mL, and 0.0625 μg/mL, respectively. SPK-843 exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis. SPK-843 can be used for the research of related fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 143483-67-4
- Formula: C67H103N5O19
- Molecular Weight:1282.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 143483-67-4
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Molecular Weight 1282.56
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Formula C67H103N5O19
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SMILES
O=C([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@]([C@@H](C)CCC(O)CC(C2=CC=C(NC)C=C2)=O)([H])OC3=O)O[C@@](O[C@H](C)[C@@H](O)[C@@H]4NC(CN(C)C)=O)([H])[C@H]4O)([H])O[C@](O)(C[C@H](C[C@H](C[C@H](C[C@H](CC(C[C@H](C3)O)=O)O)O)O)O)C[C@@H]1O)NCCN(C)C
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Synonyms
SPA-S-753 free base
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SPK-843 Related Classifications
HY-109125 Related Classifications
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