Bicd1 - BICD cargo adaptor 1 Gene

Also Known as bic-D 1; B830009D06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12121

Summary

Enables proteinase activated receptor binding activity. Involved in several processes, including negative regulation of Phospholipase C activity; regulation of signal transduction; and stress granule assembly. Predicted to be located in several cellular components, including centrosome; perinuclear region of cytoplasm; and trans-Golgi network. Predicted to be active in Golgi apparatus and cytosol. Predicted to colocalize with cytoplasmic microtubule. Is expressed in several structures, including gut; heart; nervous system; reproductive system; and sensory organ. Orthologous to human BICD1 (BICD cargo adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Bicd1 Products (2)

mRNA Protein Name
NM_001112796.2 NP_001106267.1 protein bicaudal D homolog 1 isoform 1
NM_009753.4 NP_033883.2 protein bicaudal D homolog 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32079660 MGI
enables proteinase activated receptor binding IPI
IPI: Inferred from physical interaction
20164183 MGI
Biological Process GO Annotation Evidence References Source
involved in microtubule anchoring at microtubule organizing center IMP
IMP: Inferred from mutant phenotype
19825938 MGI
involved in negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
20164183 MGI
involved in stress granule assembly IMP
IMP: Inferred from mutant phenotype
19825938 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein bicaudal D homolog 1

  • bicaudal D homolog 1

Bicd1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Bicd1 Q8BR07 Ptpn23 Mus musculus Q6PB44
Confocal
32079660
Intra
Bicd1 Q8BR07 Ptpn23 Mus musculus Q6PB44
Anti Bait CoIP
32079660
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01498 BICD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bicd1 NCBI NCBI:636