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PSI-697 (Synonyms: P-Selectin Inhibitor)

Cat. No.: HY-15526 Purity: 99.61%
Handling Instructions

PSI-697is a P-selectin inhibitor.

For research use only. We do not sell to patients.

PSI-697 Chemical Structure

PSI-697 Chemical Structure

CAS No. : 851546-61-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 340 In-stock
Estimated Time of Arrival: December 31
1 mg USD 168 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References


PSI-697is a P-selectin inhibitor. In vivo: 30 mg/kg; oral gavage daily. Animals treaed with PSI-697 shows a significantly decreased intimal thickness score when compared with vehicle control IVCs. PSI-697 significantly decreased vein wall levels of platelet-derived growth factor . d PSI-697 inhibits vein wall injury independently of thrombus mass. P-selectin inhibition seemed superior to LMWH in measured parameters of injury and mediator inhibition. PSI-697 inhibit vein wall injury independently of thrombus size in a rodent model of DVT. [1] PSI-697 (50 mg/kg p.o.) significantly reduced the number of rolling leukocytes by 39% (P < 0.05) versus vehicle control. In a rat venous thrombosis model, PSI-697 (100 mg/kg p.o.) reduced thrombus weight by 18% (P < 0.05) relative to vehicle, without prolonging bleeding time. [2] Animals receiving PSI-697 demonstrated significantly increased plasma D-dimer levels versus LMWH and control animals six hours post thrombus induction.[3]

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 45.8 mg/mL (124.51 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7186 mL 13.5932 mL 27.1865 mL
5 mM 0.5437 mL 2.7186 mL 5.4373 mL
10 mM 0.2719 mL 1.3593 mL 2.7186 mL
*Please refer to the solubility information to select the appropriate solvent.
Molecular Weight








Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

Room temperature in continental US; may vary elsewhere

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Cat. No.: HY-15526