1 Result for "

TCS-PIM-1-4a

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TCS-PIM-1-4a" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-16576A
CAS No.: 438190-29-5
Synonyms: TCS-PIM-1-4a
Target:  

Pim

Research Areas:  

Cancer

SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. SMI-4a also inhibits Pim-2 (IC50 of 100 μM), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity .
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