1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. AcBut

AcBut 

Cat. No.: HY-128969
Handling Instructions

AcBut is a pH cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

AcBut Chemical Structure

AcBut Chemical Structure

CAS No. : 400046-53-9

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Description

AcBut is a pH cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Alkyl/ether

 

Molecular Weight

1681.68

Formula

C₇₃H₉₇IN₆O₂₅S₃

CAS No.

400046-53-9

SMILES

C/C(C1=CC=C(OCCCC(N)=O)C=C1)=N\NC(CC(C)(C)SSC/C=C2C([[email protected]](C#C/C=C\C#C[[email protected]@]\2(C3)O)O[[email protected]@]4([H])[[email protected]@H]([[email protected]]([[email protected]](NO[[email protected]]5C[[email protected]@H]([[email protected]](SC(C6=C(C(OC)=C(O[[email protected]]7[[email protected]@H]([[email protected]@H]([[email protected]@H](O)[[email protected]](C)O7)OC)O)C(I)=C6C)OC)=O)[[email protected]@H](C)O5)O)[[email protected]@H](C)O4)O)O[[email protected]@]8([H])C[[email protected]@H]([[email protected]@H](N(CC)C(C)=O)CO8)OC)=C(NC(OC)=O)C3=O)=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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AcBut
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