SF20 Antibody
(Synonyms: IL25, IL27, SF20, IL27w, C19orf10)SF20 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to SF20.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH7.4).
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1-5 µL/mg of lysate |
Product Details
SF20 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to SF20.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 15 kDa;
Recombinant protein of Human SF20
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4).
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SF20 is a Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis[1].
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Subcellular Localization
Secreted; Endoplasmic reticulum-Golgi intermediate compartment; Endoplasmic reticulum; Golgi apparatus
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Expression
Tissue_Specificity: Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
Induction: Up-regulated in response to myocardial infarction (MI). -
Isoforms & Post-Translational Modification
SF20 has an amino acid length of 173, molecular weight is 18795 Da.
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SwissProt ID
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Synonyms
IL25, IL27, SF20, IL27w, C19orf10
Documentation
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