STAB2 Antibody (YA7959)
(Synonyms: FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1)STAB2 Antibody (YA7959) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAB2.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P
-
Reactivity :
Human
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
STAB2 Antibody (YA7959) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAB2.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 274.7 kDa
Human recombinant protein fragment corresponding to amino acids 1914-2194 of human STAB2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
STAB2 is a Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Also acts, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS
-
Subcellular Localization
Cell membrane,Cytoplasm
-
Expression
Tissue_Specificity: Highly expressed in sinusoidal endothelial cells of liver, spleen and lymph nodes. Also expressed in non SEC-cells such as HMDMs (monocyte-derivedmacrophages), HAMs (T-cell leukemia virus type 1-associated myelopathy), and several macrophage cell line -
Isoforms & Post-Translational Modification
Q8WWQ8: 2551 amino acids, molecular weight 276988 Da.
-
Subunit
Interacts with GULP1 and heparin
-
SwissProt ID
-
Synonyms
FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1
Documentation
Powered by Bioz
