SYNC Antibody (YA8777)

Cat. No.: HY-P89093: Data Sheet User Guide for Antibodies
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SYNC Antibody (YA8777) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYNC.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SYNC Antibody (YA8777) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYNC.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 17.7 kDa

Species Reactivity

Human

SwissProt ID

Q9H7C4

Immunogen

Full length human recombinant protein of human SYNC produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins

Subcellular Localization：Cytoplasm, perinuclear region

Expression：Induction: Up-regulated at the sarcolemma in individuals with various forms of neuromuscular disease

Isoforms & Post-Translational Modification：Q9H7C4 has two isomers: Q9H7C4-1: 55299 Da (predicted); Q9H7C4-2: 54947 Da (predicted).

Subunit：May link the dystrophin-associated glycoprotein complex (DAPC) to intracellular desmin (DES) filaments

Synonyms

SYNC1; SYNCOILIN

Documentation

User Guide for Antibodies (1077 KB)