SYNC Antibody (YA8777)
(Synonyms: SYNC1; SYNCOILIN)SYNC Antibody (YA8777) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYNC.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
SYNC Antibody (YA8777) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYNC.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 17.7 kDa
Full length human recombinant protein of human SYNC produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SYNC is an Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins
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Subcellular Localization
Cytoplasm, perinuclear region
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Expression
Induction: Up-regulated at the sarcolemma in individuals with various forms of neuromuscular disease
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Isoforms & Post-Translational Modification
Q9H7C4 has two isomers: Q9H7C4-1: 55299 Da (predicted); Q9H7C4-2: 54947 Da (predicted).
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Subunit
May link the dystrophin-associated glycoprotein complex (DAPC) to intracellular desmin (DES) filaments
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SwissProt ID
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Synonyms
SYNC1; SYNCOILIN
Documentation
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