80681-58-9
80681-58-9
Chemical Structure
2’,3’,5’-Tri-O-acetyl-6-S-methyl-6-thio-guanosine
- CAS. Nr.: 80681-58-9
- Formula:C17H22N5O7S
- Molecular Weight:440.45
IUPAC Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-amino-6-(methylthio)-1l2-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate
InChIKey: VWFJEUCYMGRFPH-MIWZLHRFSA-N
SMILES: O=C(C)O[C@H]1[C@@H](OC(C)=O)[C@H](N2C(N=C(N)[N]C3SC)=C3N=C2)O[C@@H]1COC(C)=O
Biological Activity: 2’,3’,5’-Tri-O-acetyl-6-S-methyl-6-thio-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’,3’,5’-Tri-O-acetyl-6-S-methyl-6-thio-guanosine | 2’,3’,5’-Tri-O-acetyl-6-S-methyl-6-thio-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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