Adra1b - adrenoceptor alpha 1B Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24173

Summary

Enables alpha1-adrenergic receptor activity. Involved in several processes, including positive regulation of cytosolic calcium ion concentration; response to estrogen; and response to steroid hormone. Acts upstream of or within negative regulation of Rho protein signal transduction. Located in T-tubule and intercalated disc. Biomarker of polycystic ovary syndrome. Orthologous to human ADRA1B (adrenoceptor alpha 1B). [provided by Alliance of Genome Resources, Apr 2022]

Adra1b Products (1)

mRNA Protein Name
NM_016991.2 NP_058687.2 alpha-1B adrenergic receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables alpha1-adrenergic receptor activity IDA
IDA: Inferred from direct assay
12054611 RGD
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within negative regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
18332105 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12054611 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
11896179 RGD
involved in response to hormone IMP
IMP: Inferred from mutant phenotype
12270752 RGD
involved in response to steroid hormone IMP
IMP: Inferred from mutant phenotype
12818703 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16309668 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in T-tubule IDA
IDA: Inferred from direct assay
18467629 RGD
located in intercalated disc IDA
IDA: Inferred from direct assay
18467629 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1B adrenergic receptor

  • Adrenergic alpha 1B- receptor

  • adrenergic receptor, alpha 1b

  • adrenergic, alpha-1B-, receptor

  • alpha-1B adrenoceptor

  • alpha-1B adrenoreceptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00409 ADRA1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adra1b NCBI NCBI:147