EPC2 - enhancer of polycomb homolog 2 Gene

Also Known as EPC-LIKE

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26122

About EPC2

Cytogenetic location: 2q23.1 Genomic coordinates (GRCh38): 2:148,644,751-148,787,569 (from NCBI)

This gene has 6 transcripts (splice variants), 184 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 10.6), endometrium (RPKM 9.8) and 25 other tissues.

Summary

Predicted to contribute to Histone Acetyltransferase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of Piccolo NuA4 Histone Acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

EPC2 Products (1)

mRNA Protein Name
NM_015630.4 NP_056445.3 enhancer of polycomb homolog 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in positive regulation of double-strand break repair via homologous recombination IDA
IDA: Inferred from direct assay
27153538 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
27153538 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of NuA4 histone acetyltransferase complex IDA
IDA: Inferred from direct assay
27153538 GOA
part of nucleosome IDA
IDA: Inferred from direct assay
27153538 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

enhancer of polycomb homolog 2

Related Diseases

Diseases Alias
Mbd5 Haploinsufficiency

  • 2q23.1 Microdeletion Syndrome

  • 2q23.1 Microduplication Syndrome

  • Del(2)(Q23.1)

  • Monosomy 2q23.1

  • Pseudo-Angelman Syndrome

  • Mbd5 Associated Neurodevelopmental Disorder

  • Chromosome 2q23.1 Microdeletion Syndrome

  • Mbd5-Associated Neurodevelopmental Disorder

  • Mand

  • Dup(2)(Q23.1)

  • Trisomy 2q23.1
Bile Reflux
Esophagitis, Eosinophilic, 1

  • Eosinophilic Esophagitis

  • EOE1

  • Esophagitis, Eosinophilic

  • Ee
Endometrial Stromal Tumor

  • Endometrial Stromal Neoplasm

  • Endometrial Stromal Tumors
Endometrial Stromal Sarcoma

  • Ess

  • Endometrial Stromal Sarcoma, High Grade

  • Undifferentiated Endometrial Sarcoma

  • Stromal Sarcoma Of The Corpus Uteri

  • Sarcoma Endometrial Stromal

  • Sarcoma, Endometrial Stromal

  • Undifferentiated Stromal Sarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04419 EPC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EPC2 VGNC VGNC:72096
Rattus norvegicus EPC2 RGD RGD:1307271
Felis catus EPC2 VGNC VGNC:61899
Mus musculus EPC2 MGD MGI:1278321
Bos taurus EPC2 VGNC VGNC:28528
Canis familiaris EPC2 VGNC VGNC:40401
Others EPC2 NCBI