Prpf19 - pre-mRNA processing factor 19 Gene

Also Known as PSO4; Snev; Prp19; NMP200; D19Wsu55e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28000

Summary

Predicted to enable identical protein binding activity and ubiquitin-ubiquitin Ligase activity. Involved in proteasomal protein catabolic process. Acts upstream of or within several processes, including inner cell mass cell proliferation; positive regulation of astrocyte differentiation; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in several structures, including extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19). [provided by Alliance of Genome Resources, Apr 2022]

Prpf19 Products (3)

mRNA Protein Name
NM_001253843.1 NP_001240772.1 pre-mRNA-processing factor 19 isoform 1
NM_001253844.1 NP_001240773.1 pre-mRNA-processing factor 19 isoform 3
NM_134129.4 NP_598890.1 pre-mRNA-processing factor 19 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
17349974 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within lipid biosynthetic process IDA
IDA: Inferred from direct assay
17118936 MGI
acts upstream of or within positive regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
18480465 MGI
involved in proteasomal protein catabolic process IMP
IMP: Inferred from mutant phenotype
17349974 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
18480465 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-processing factor 19

  • PRP19/PSO4 homolog

  • PRP19/PSO4 pre-mRNA processing factor 19 homolog

  • RING-type E3 ubiquitin transferase PRP19

  • nuclear matrix protein 200

  • nuclear matrix protein SNEV

  • prp19 beta

  • senescence evasion factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11206 PRPF19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prpf19 NCBI NCBI:27339