Gpam - glycerol-3-phosphate acyltransferase, mitochondrial Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29653

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Involved in several processes, including glycerolipid biosynthetic process; positive regulation of triglyceride biosynthetic process; and response to fructose. Located in mitochondrial outer membrane. Biomarker of nephrotic syndrome and obesity. Orthologous to human GPAM (glycerol-3-phosphate Acyltransferase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Gpam Products (1)

mRNA Protein Name
NM_017274.1 NP_058970.1 glycerol-3-phosphate acyltransferase 1, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables glycerol-3-phosphate O-acyltransferase activity IDA
IDA: Inferred from direct assay
10446428 RGD
enables glycerol-3-phosphate O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
22905194 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in cellular response to insulin stimulus IDA
IDA: Inferred from direct assay
18167308 RGD
involved in diacylglycerol biosynthetic process IMP
IMP: Inferred from mutant phenotype
22905194 RGD
involved in phosphatidic acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
22905194 RGD
involved in positive regulation of triglyceride biosynthetic process IDA
IDA: Inferred from direct assay
15598672 RGD
involved in response to activity IDA
IDA: Inferred from direct assay
16234267 RGD
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
17066326 RGD
involved in response to fructose IEP
IEP: Inferred from expression pattern
19053045 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
26394137 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
18493788 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
18167308 RGD
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
17493869 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate acyltransferase 1, mitochondrial

  • GPAT

  • GPAT-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS05615 GPAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20747 Gpam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27259 Gpam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpam NCBI NCBI:57678