Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene
Species: Rattus norvegicus
Summary
Predicted to enable identical protein binding activity; nicotinamide-nucleotide adenylyltransferase activity; and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Located in cytoplasm and nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Nmnat1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001037556.2 | NP_001032645.2 | nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-W615108B | β-Nicotinamide mononucleotide, reduced form disodium | 99.55% | Unkown | |
| HY-161712 | IMPDH-IN-4 | Inhibitor | 99.76% | Unkown |
| HY-RS09382 | NMNAT1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18008 | Nmnat1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24481 | Nmnat1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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