BAIAP2L2 - BAR/IMD domain containing adaptor protein 2 like 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80115

About BAIAP2L2

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,084,900-38,110,967 (from NCBI)

This gene has 7 transcripts (splice variants), 233 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 28.1), small intestine (RPKM 24.8) and 4 other tissues.

Summary

The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. [provided by RefSeq, Dec 2012]

BAIAP2L2 Products (1)

mRNA Protein Name
NM_025045.6 NP_079321.3 brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence Verweise Source
located in cell-cell contact zone IDA
IDA: Inferred from direct assay
21743456 GOA
part of clathrin complex IDA
IDA: Inferred from direct assay
21401524 GOA
located in vesicle membrane IDA
IDA: Inferred from direct assay
21743456 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BAIAP2L2 Protein Structure

IMD

IMD: IRSp53/MIM homology domain (16 - 226)

SH3_9

SH3_9: Variant SH3 domain (339 - 383)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 529 a.a.
Protein Preferred Names Protein Names

brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2

  • BAI1 associated protein 2 like 2

Related Diseases

Diseases Alias
Autosomal Dominant Nonsyndromic Deafness 78

  • Dfna78
Deafness, Autosomal Recessive 28

  • DFNB28

  • Autosomal Recessive Nonsyndromic Deafness 28

  • Autosomal Recessive Deafness 28

  • Deafness, Autosomal Recessive, 28

  • Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 28

  • Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 28

  • Deafness, Autosomal Recessive, Type 28
Branchiootorenal Syndrome 1

  • Melnick-Fraser Syndrome

  • BOR1

  • Branchiootorenal Dysplasia

  • Branchiootorenal Syndrome 1, With Or Without Cataracts

  • Bor Syndrome 1

  • Branchiootorenal Dysplasia 1

  • Branchio-Oto-Renal Dysplasia 1

  • Branchio-Oto-Renal Syndrome Type 1

  • Branchiootorenal Syndrome, With/Without Cataract, Type 1

  • Branchio-Oto-Renal Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01355 BAIAP2L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BAIAP2L2 MGD MGI:2652819
Bos taurus BAIAP2L2 VGNC VGNC:26414
Felis catus BAIAP2L2 VGNC VGNC:60072
Canis familiaris BAIAP2L2 VGNC VGNC:38373
Rattus norvegicus BAIAP2L2 RGD RGD:1595091
Macaca mulatta BAIAP2L2 VGNC VGNC:70133
Others BAIAP2L2 NCBI