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Art. -Nr.: HY-106580A

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Plafibride hydrochloride

(Synonyms: ITA 104 hydrochloride)

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor.

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CAS. Nr.: 65285-81-6
Formel: C₁₆H₂₃Cl₂N₃O₄
Molecular Weight:392.28

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Plafibride hydrochloride Chemical Structure

CAS. Nr.: 65285-81-6

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Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor^[1]^[2].

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Retinol Binding Protein

In Vivo

Plafibride (100 mg/kg, p.o.) hydrochloride shows marked platelet anti-aggregant activity in rabbits^[1].
Plafibride hydrochloride has low toxicity, with LD₅₀s of about 4000 mg/kg (p.o.) in rat, mouse and hamster^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rabbit^[1]
Dosage:

100 mg/kg
Administration:

Oral administration (p.o.)
Result:

Induced platelet aggregation.

Chemical Information

CAS. Nr. 65285-81-6
Molecular Weight 392.28
Formel C₁₆H₂₃Cl₂N₃O₄
SMILES

O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(C=C2)Cl)=O.Cl
Synonyms

ITA 104 hydrochloride
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]

[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
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- In Vivo
Chemical Information
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Plafibride hydrochloride

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Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Plafibride hydrochloride Related Classifications

HY-106580A Related Classifications