193 Results for "

macrolides

" in MedChemExpress (MCE) Product Catalog:
Products (193)

193 Results for "macrolides" in MCE Product Catalog:

815
Bafilomycin A1
Bafilomycin A1
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815 Publications Verification
Art. -Nr.: HY-100558
CAS. Nr.: 88899-55-2
Reinheit:  99.95%
Synonyms: BafA1
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Anticancer Disease Research Fields

Target:  

Proton Pump Autophagy Antibiotic Bacterial Apoptosis

Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H +-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .
48
Filipin complex
Filipin complex
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48 Cited Publications
Art. -Nr.: HY-N6716
CAS. Nr.: 11078-21-0
Category:  

Microorganisms Antifungal Antibiotics Other Diseases Antiviral Disease Research Disease Research Fields Other Antibiotics

Target:  

Fungal Antibiotic

Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
45
Azithromycin
Azithromycin
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45 Cited Publications
Art. -Nr.: HY-17506
CAS. Nr.: 83905-01-5
Synonyms: CP 62993
Target:  

Bacterial Autophagy Antibiotic Parasite

Forschungsgebiete:  

Infection Cancer

Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
45
Azithromycin hydrate
Azithromycin hydrate
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45 Cited Publications
Art. -Nr.: HY-17506A
CAS. Nr.: 117772-70-0
Synonyms: CP-62993 dihydrate
Target:  

Bacterial Autophagy Antibiotic Parasite

Forschungsgebiete:  

Infection Cancer

Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
28
Concanamycin A
Concanamycin A
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28 Cited Publications
Art. -Nr.: HY-N1724
CAS. Nr.: 80890-47-7
Synonyms: Antibiotic X 4357B; Folimycin; X 4357B
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

Proton Pump Bacterial Antibiotic

Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
24
Filipin III
Filipin III
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24 Cited Publications
Art. -Nr.: HY-N6718
CAS. Nr.: 480-49-9
Category:  

Microorganisms Antifungal Antibiotics Disease Research Disease Research Fields Inflammation/Immunology Other Antibiotics

Target:  

Antibiotic Fungal

Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .
24
Erythromycin
Erythromycin
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24 Cited Publications
Art. -Nr.: HY-B0220
CAS. Nr.: 114-07-8
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Disease Research Antibacterial Anticancer Disease Research Fields

Target:  

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
24
Erythromycin lactobionate
Erythromycin lactobionate
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24 Cited Publications
Art. -Nr.: HY-B0220A
CAS. Nr.: 3847-29-8
Target:  

Antibiotic Bacterial DNA/RNA Synthesis

Forschungsgebiete:  

Infection Cancer

Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
24
Erythromycin thiocyanate
Erythromycin thiocyanate
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24 Cited Publications
Art. -Nr.: HY-B0220D
CAS. Nr.: 7704-67-8
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields

Target:  

Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
24
Erythromycin (Standard)
Erythromycin (Standard)
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24 Cited Publications
Art. -Nr.: HY-B0220R
CAS. Nr.: 114-07-8
Category:  

Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields

Target:  

Reference Standards Bacterial Antibiotic DNA/RNA Synthesis

Erythromycin (Standard) is the analytical standard of Erythromycin. This product is intended for research and analytical applications. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid . Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research .
8
Natamycin
Natamycin
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8 Cited Publications
Art. -Nr.: HY-B0133
CAS. Nr.: 7681-93-8
Synonyms: Pimaricin
Category:  

Preservatives Antifungal Anti-inflammation/Immunoregulatory Disease Research Endogenous metabolite Food Research Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Fields

Target:  

Environmental Pollutants Antibiotic Endogenous Metabolite Fungal Bacterial

Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .
7
Roxithromycin
Roxithromycin
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7 Cited Publications
Art. -Nr.: HY-B0435
CAS. Nr.: 80214-83-1
Synonyms: RU-28965
Target:  

Bacterial Antibiotic Apoptosis p38 MAPK NF-κB

Forschungsgebiete:  

Infection Cardiovascular Disease Inflammation/Immunology Cancer

Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects .
6
Ascomycin
Ascomycin
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6 Cited Publications
Art. -Nr.: HY-13557
CAS. Nr.: 104987-12-4
Reinheit:  ≥98.0%
Synonyms: Immunomycin; FR-900520; FK520
Category:  

Microorganisms Neurological Disease Macrolide Antibiotics Antifungal Anti-inflammation/Immunoregulatory Antibiotics Disease Research Disease Research Fields Inflammation/Immunology

Target:  

FKBP Parasite Fungal Antibiotic

Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .
5
Telithromycin
Telithromycin
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5 Cited Publications
Art. -Nr.: HY-A0062
CAS. Nr.: 191114-48-4
Synonyms: HMR3647; RU66647
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection Inflammation/Immunology

Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
5
Tilmicosin
Tilmicosin
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5 Cited Publications
Art. -Nr.: HY-B0905
CAS. Nr.: 108050-54-0
Synonyms: LY-177370; EL-870
Target:  

Bacterial Antibiotic Apoptosis Calcium Channel

Forschungsgebiete:  

Infection Inflammation/Immunology

Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .
5
Tilmicosin phosphate
Tilmicosin phosphate
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5 Cited Publications
Art. -Nr.: HY-B0905A
CAS. Nr.: 137330-13-3
Synonyms: LY-177370 phosphate; EL-870 phosphate
Target:  

Bacterial Antibiotic Apoptosis NO Synthase COX

Forschungsgebiete:  

Infection Inflammation/Immunology

Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects .
5
Pladienolide B
Pladienolide B
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5 Cited Publications
Art. -Nr.: HY-16399
CAS. Nr.: 445493-23-2
Target:  

Apoptosis SF3B1

Forschungsgebiete:  

Cancer

Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis .
2
Bryostatin 1
Bryostatin 1
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2 Cited Publications
Art. -Nr.: HY-105231
CAS. Nr.: 83314-01-6
Reinheit:  99.70%
Category:  

Neurological Disease Anti-inflammation/Immunoregulatory Marine natural products Other marine organisms Disease Research Infection Animals Macrolide Antibiotics Antibiotics Anticancer Disease Research Fields Inflammation/Immunology

Target:  

PKC HIV Bacterial

Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties .
2
Tylvalosin tartrate
Tylvalosin tartrate
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2 Cited Publications
Art. -Nr.: HY-128423
CAS. Nr.: 63428-13-7
Reinheit:  98.77%
Synonyms: Acetylisovaleryltylo​sin tartrate
Target:  

Antibiotic Bacterial NF-κB Apoptosis

Forschungsgebiete:  

Infection Inflammation/Immunology

Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .
2
Midecamycin
Midecamycin
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2 Cited Publications
Art. -Nr.: HY-B1908
CAS. Nr.: 35457-80-8
Synonyms: SF-837; Antibiotic SF-837
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Disease Research Fields

Target:  

Bacterial Antibiotic

Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
Assay Types