480-49-9
480-49-9
Chemical Structure
Filipin III
- CAS No.: 480-49-9
- Formula:C35H58O11
- Molecular Weight:654.83
IUPAC Name: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-((R)-1-hydroxyhexyl)-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one
InChIKey: IMQSIXYSKPIGPD-YQRUMEKGSA-N
SMILES: O=C1O[C@H](C)[C@@H](O)/C=C/C=C/C=C/C=C/C=C(C)/[C@@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)[C@H]1[C@H](O)CCCCC
Biological Activity: Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Filipin III | 98.39% | Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. | ||||||||||||||||||||
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Filipin III (Standard) | ≥98% | Filipin III (Standard) is the analytical standard of Filipin III (HY-N6718). This product is intended for research and analytical applications. Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. | ||||||||||||||||||||
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Lagosin | 96.14% | Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance. | ||||||||||||||||||||
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RK 397 | RK 397 is an active compound. | |||||||||||||||||||||
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Filipin II | Filipin II is an antibiotic, which exhibits antifungal efficacy. Filipin II interacts with membrane sterols, leads to changes in membrane structure, inhibits Candida utilis and Saccharomyces cerevisiae with the MIC of 0.03 mg/L and 0.2 μg/L. | |||||||||||||||||||||
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Antibiotic AB023a | Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum. | |||||||||||||||||||||
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Antibiotic AB023b | Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum. | |||||||||||||||||||||
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Elizabethin | Elizabethin has antifungal activity. | |||||||||||||||||||||
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Dermostatin A | Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections. | |||||||||||||||||||||
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Dermostatin B | Dermostatin B is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections. | |||||||||||||||||||||
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Chainin | Chainin has anti-yeast and Aspergillus Niger fungal activity. | |||||||||||||||||||||
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Strevertene A | Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants. | |||||||||||||||||||||
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