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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
paracetamol
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "paracetamol" in MCE Product Catalog:
74
74 Publications Verification
Synonyms: paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide
74
74 Publications Verification
Synonyms: paracetamol (Standard); 4-Acetamidophenol (Standard); 4'-Hydroxyacetanilide (Standard)
Forschungsgebiete:
Acetaminophen (Standard) is the analytical standard of Acetaminophen. This product is intended for research and analytical applications. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
2
2 Cited Publications
Synonyms: APAP-Cys TFA
Target:
Forschungsgebiete:
Paracetamol-cysteine (TFA) is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005) .
1
Target:
Forschungsgebiete:
Benorylate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid. Benorylate has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis .
Art. -Nr.: HY-66005S
CAS. Nr.: 64315-36-2
Synonyms: paracetamol-d4; 4-Acetamidophenol-d4; 4'-Hydroxyacetanilide-d4
Art. -Nr.: HY-W015600
CAS. Nr.: 614-80-2
Synonyms: Orthocetamol
Forschungsgebiete:
2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Target:
Forschungsgebiete:
Propacetamol hydrochloride is an orally active prodrug of paracetamol and an inducer of acute liver injury models, with multiple properties including antinociception, antioxidation and gastroprotection. Propacetamol hydrochloride potentiates Tramadol and attenuates Aspirin (HY-14654)-induced gastric mucosal damage and lipid peroxidation. Under specific conditions, Propacetamol hydrochloride also acts as a hepatotoxic inducer, triggering acute liver injury, oxidative stress and apoptosis, with strain differences in toxicity sensitivity. Propacetamol hydrochloride can be used in the research of acute liver injury, drug-induced hepatotoxicity and gastric mucosal damage .
Art. -Nr.: HY-66005S1
CAS. Nr.: 60902-28-5
Synonyms: paracetamol-d3; 4-Acetamidophenol-d3; 4'-Hydroxyacetanilide-d3
Target:
Forschungsgebiete:
Propacetamol is an orally active prodrug of Acetaminophen (HY-66005), which exerts antipyretic and analgesic effects after metabolism. Propacetamol reduces Aspirin (ASA) (HY-14654)-induced elevation of malondialdehyde (MDA) in gastric mucosa and plasma, regulates the levels of gastric mucosal glutathione (GSH and GSSG) to maintain cellular antioxidant defense, and increases gastric mucosal uric acid (UA) levels. Propacetamol exerts a dose-dependent protective effect against ASA-induced gastric mucosal damage in rats. Propacetamol can be used for the study of gastric mucosal injury by interfering with oxidative stress .
Art. -Nr.: HY-66005S2
CAS. Nr.: 1219798-53-4
Synonyms: paracetamol-d7; 4-Acetamidophenol-d7; 4'-Hydroxyacetanilide-d7
Art. -Nr.: HY-W015600R
CAS. Nr.: 614-80-2
Synonyms: Orthocetamol (Standard)
Forschungsgebiete:
2-Acetamidophenol (Standard) is the analytical standard of 2-Acetamidophenol. This product is intended for research and analytical applications. 2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Art. -Nr.: HY-139093
CAS. Nr.: 53446-10-9
Synonyms: APAP-Cys
Target:
Forschungsgebiete:
Art. -Nr.: HY-66005S4
CAS. Nr.: 360769-21-7
Synonyms: paracetamol-13C2,15N; 4-Acetamidophenol-13C2,15N; 4'-Hydroxyacetanilide-13C2,15N
Art. -Nr.: HY-107795R
CAS. Nr.: 5003-48-5
Synonyms: Salipran (Standard)
Forschungsgebiete:
Benorilate (Standard) is the analytical standard of Benorilate. This product is intended for research and analytical applications. Benorylate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid. Benorylate has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis .
Art. -Nr.: HY-W015600S
CAS. Nr.: 122258-87-1
Synonyms: Orthocetamol-d3
Art. -Nr.: HY-W016034
CAS. Nr.: 120595-80-4
Synonyms: p-Acetamidophenyl β-D-glucuronide sodium salt; p-AAPG sodium salt
Target:
Forschungsgebiete:
Acetaminophen glucuronide is a safe and effective
antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver
and kidney .
Art. -Nr.: HY-W042159
CAS. Nr.: 3964-54-3
Target:
Forschungsgebiete:
Paracetamol impurity 1 is an impurity of Paracetamol.
Art. -Nr.: HY-66005S3
CAS. Nr.: 2132405-57-1
Synonyms: paracetamol-13C6; 4-Acetamidophenol-13C6; 4'-Hydroxyacetanilide-13C6
Target:
Forschungsgebiete:
4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent .
Art. -Nr.: HY-W739619
CAS. Nr.: 2470331-44-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
