1331891-93-0
1331891-93-0
Chemical Structure
Paracetamol-cysteine TFA
Synonym(s): APAP-Cys TFA
- CAS No.: 1331891-93-0
- Formula:C13H15F3N2O6S
- Molecular Weight:384.33
IUPAC Name: S-(5-acetamido-2-hydroxyphenyl)-L-cysteine compound with 2,2,2-trifluoroacetic acid (1:1)
InChIKey: PDZGEXMJHANKLR-QRPNPIFTSA-N
SMILES: N[C@@H](CSC1=CC(NC(C)=O)=CC=C1O)C(O)=O.OC(C(F)(F)F)=O
Biological Activity: Paracetamol-cysteine TFA (APAP-Cys TFA) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Paracetamol-cysteine TFA | 99.9% | Paracetamol-cysteine TFA (APAP-Cys TFA) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI). | ||||||||||||||||||||
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Paracetamol-cysteine-d5 TFA | Paracetamol-cysteine-d5 TFA is the deuterium labeled Paracetamol-cysteine TFA (HY-139093A). Paracetamol-cysteine TFA is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005). | |||||||||||||||||||||
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References
- [1]. Frey SM, et al. Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts. Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2015 Jun;11(2):218-22.
- [2]. Heard K, et al. Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing. Br J Clin Pharmacol. 2016 Mar;81(3):562-8. [Content Brief]
