Neil1 - nei endonuclease VIII-like 1 (E. coli) Gene

Also Known as NEH1; Nei1; 2810450N13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72774

Summary

Enables DNA N-glycosylase activity and lyase activity. Acts upstream of or within DNA repair. Located in nucleus. Is expressed in ductus deferens; embryo; epididymis; and metanephros. Used to study abdominal obesity-metabolic syndrome and obesity. Orthologous to human NEIL1 (nei like DNA glycosylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Neil1 Products (2)

mRNA Protein Name
NM_001357409.1 NP_001344338.1 endonuclease 8-like 1 isoform 2
NM_028347.3 NP_082623.1 endonuclease 8-like 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
12200441 MGI
enables lyase activity IDA
IDA: Inferred from direct assay
12200441 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA repair IDA
IDA: Inferred from direct assay
12200441 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12200441 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endonuclease 8-like 1

  • DNA glycosylase/AP lyase Neil1

  • DNA-(apurinic or apyrimidinic site) lyase Neil1

  • endonuclease VIII

  • endonuclease VIII-like 1

  • nei homolog 1

  • nei-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09187 NEIL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19723 Neil1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26219 Neil1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neil1 NCBI NCBI:79661