Forkhead box protein P3
Definition:
References:
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[1]. Fred Ramsdell, et al. FOXP3 and scurfy: how it all began. Nat Rev Immunol. 2014 May;14(5):343-9. [Content Brief]
[2]. Jens Vent-Schmidt, et al. The role of FOXP3 in regulating immune responses. Int Rev Immunol. 2014 Mar;33(2):110-28. [Content Brief]
[3]. Laura Passerini, et al. Forkhead box P3: the peacekeeper of the immune system. Int Rev Immunol. 2014 Mar;33(2):129-45. [Content Brief]
[4]. Masahiro Ono, et al. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature. 2007 Apr 5;446(7136):685-9. [Content Brief]
[5]. Alicia N McMurchy, et al. A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells. Blood. 2013 Feb 21;121(8):1265-75. [Content Brief]
[6]. Jianguang Du, et al. Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3. J Immunol. 2008 Apr 1;180(7):4785-92. [Content Brief]
[7]. Liang Zhou, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 2008 May 8;453(7192):236-40. [Content Brief]
[8]. Hozefa S Bandukwala, et al. Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity. 2011 Apr 22;34(4):479-91. [Content Brief]
[9]. Juliane Becher, et al. AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis. Dev Cell. 2018 Dec 3;47(5):592-607.e6. [Content Brief]
[10]. Bin Li, et al. FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4571-6. [Content Brief]
[11]. Yan Xiao, et al. Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. Cell Rep. 2014 Jun 12;7(5):1471-1480. [Content Brief]
[12]. Estelle Bettelli, et al. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5138-43. [Content Brief]
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