Golgi pH regulator A
Definition:
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity).
References:
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[1]. Yusuke Maeda, et al. GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. Nat Cell Biol. 2008 Oct;10(10):1135-45. [Content Brief]
[2]. Akio Matsuda, et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene. 2003 May 22;22(21):3307-18. [Content Brief]
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