SLC44A5 - solute carrier family 44 member 5 Gene

Also Known as CTL5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 204962

About SLC44A5

This gene has 3 transcripts (splice variants), 248 orthologues and 4 paralogues. Broad expression in skin (RPKM 2.6), testis (RPKM 1.3) and 21 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC44A5 Products (6)

mRNA Protein Name
NM_001130058.2 NP_001123530.1 choline transporter-like protein 5 isoform B
NM_001320283.3 NP_001307212.1 choline transporter-like protein 5 isoform C
NM_001320285.2 NP_001307214.1 choline transporter-like protein 5 isoform D precursor
NM_001320287.2 NP_001307216.1 choline transporter-like protein 5 isoform D precursor
NM_001394064.1 NP_001380993.1 choline transporter-like protein 5 isoform E
NM_152697.6 NP_689910.2 choline transporter-like protein 5 isoform A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables choline transmembrane transporter activity IDA
IDA: Inferred from direct assay
23651124 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Biological Process GO Annotation Evidence References Source
involved in choline transport IDA
IDA: Inferred from direct assay
23651124 GOA
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
23651124 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC44A5 Protein Structure

Choline_transpo

Choline_transpo: Plasma-membrane choline transporter (328 - 691)

  • 0
  • 200
  • 400
  • 600
  • 719 a.a.
Protein Preferred Names Protein Names

choline transporter-like protein 5

SLC44A5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC44A5 Q8NCS7 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 BDNF Homo sapiens P23560-2
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 BDNF Homo sapiens P23560-2
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 BDNF Homo sapiens P23560-2
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 TGFBR2 Homo sapiens P37173
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 TGFBR2 Homo sapiens P37173
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 TGFBR2 Homo sapiens P37173
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 SERPINH1 Homo sapiens P50454
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 SERPINH1 Homo sapiens P50454
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 SERPINH1 Homo sapiens P50454
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 PECAM1 Homo sapiens P16284
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 PECAM1 Homo sapiens P16284
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 PECAM1 Homo sapiens P16284
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 RAD23A Homo sapiens P54725
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 RAD23A Homo sapiens P54725
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 RAD23A Homo sapiens P54725
Y2H Pooling
32814053
Intra
SLC44A5 Q8NCS7 CBX5 Homo sapiens P45973
Validated Y2H
32814053
Intra
SLC44A5 Q8NCS7 CBX5 Homo sapiens P45973
Y2H Array
32814053
Intra
SLC44A5 Q8NCS7 CBX5 Homo sapiens P45973
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Retinitis Pigmentosa 25

  • RP25

  • Retinitis Pigmentosa-25

  • Retinitis Pigmentosa, Type 25
Choline Deficiency Disease

  • Choline Deficiency
Dicarboxylic Aminoaciduria

  • Glutamate-Aspartate Transport Defect

  • Dicarboxylicaminoaciduria

  • DCBXA

  • Renal Aminoacidurias
Iminoglycinuria

  • Iminoglycinuria, Digenic

  • IG
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13255 SLC44A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC44A5 VGNC VGNC:77785
Rattus norvegicus SLC44A5 RGD RGD:1564620
Bos taurus SLC44A5 VGNC VGNC:34879
Mus musculus SLC44A5 MGD MGI:3035141
Canis familiaris SLC44A5 VGNC VGNC:46421
Felis catus SLC44A5 VGNC VGNC:65375
Others SLC44A5 NCBI