B-Raf IN 9
B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 µM.
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- CAS No.: 2477725-18-9
- Formule: C23H20N4OS
- Masse moléculaire:400.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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B-Raf 24.97 ± 0. nM (IC50) |
Chemical Information
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CAS No. 2477725-18-9
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Masse moléculaire 400.50
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Formule C23H20N4OS
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SMILES
S=C(NC1=CC=CC=C1)NC2=CC=C(C(CC3)=NN(C4=CC=CC=C4)C3=O)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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