308356-20-9
308356-20-9
Chemical Structure
N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine
- CAS No.: 308356-20-9
- Formula:C14H18FN5O5
- Molecular Weight:355.32
IUPAC Name: N-(9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
InChIKey: SLHADUUWJSVYGQ-NDORMNELSA-N
SMILES: O=C1NC(NC(C(C)C)=O)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3F
Biological Activity: N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine | N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
