CCDC28B - coiled-coil domain containing 28B Gene

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 79140

Summary

The product of this gene localizes to centrosomes and basal bodies. The protein colocalizes with several proteins associated with Bardet-Biedl syndrome (BBS) and participates in the regulation of cilia development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CCDC28B Products (1)

mRNA Protein Name
XM_054338690.1 XP_054194665.1 coiled-coil domain-containing protein 28B isoform X3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
16327777 GOA
Biological Process GO Annotation Evidence Références Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
23015189 GOA
Cellular Component GO Annotation Evidence Références Source
located in centrosome IDA
IDA: Inferred from direct assay
16327777 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 28B

CCDC28B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
CCDC28B Q9BUN5 BBS4 Homo sapiens Q96RK4
Y2H
16327777
Intra
CCDC28B Q9BUN5 BBS4 Homo sapiens Q96RK4
Anti Tag CoIP
16327777
Intra
CCDC28B Q9BUN5 ATRIP Homo sapiens Q8WXE1
Validated Y2H
25416956
Intra
CCDC28B Q9BUN5 ATRIP Homo sapiens Q8WXE1
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS02062 CCDC88B Human Pre-designed siRNA Set A Pre-designed Set / Unkown