HER2-IN-13
HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM.
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- CAS No.: 2414056-34-9
- Formule: C26H23ClF2N8O3
- Masse moléculaire:568.96
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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HER2 8 nM (IC50) |
EGFR (WT) 0.40 μM (IC50) |
hERG 13.3 μM (IC50) |
HER2-IN-13 (Compound 33) inhibits hERG channel with an IC50 of 13.3 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2414056-34-9
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Masse moléculaire 568.96
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Formule C26H23ClF2N8O3
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SMILES
ClC(C=C1NC2=NC=NC3=C2C(O[C@H]4C(F)(CN(CC4)C)F)=C(OC)C=C3)=C(C=C1)OC5=CC6=NC=NN6C=N5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HER2-IN-13 Related Classifications
HY-153557 Related Classifications
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