HER2-IN-14
HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM.
For research use only. We do not sell to patients.
- CAS No.: 2414056-35-0
- Formula: C26H23ClF2N8O3
- Molecular Weight:568.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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HER2 18 nM (IC50) |
EGFR (WT) 6.3 μM (IC50) |
Chemical Information
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CAS No. 2414056-35-0
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Molecular Weight 568.96
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Formula C26H23ClF2N8O3
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SMILES
ClC(C=C1NC2=NC=NC3=C2C(O[C@@H]4C(F)(CN(CC4)C)F)=C(OC)C=C3)=C(C=C1)OC5=CC6=NC=NN6C=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)